Guest star, Jay Leno hosts a # of comedy sketches along with Clifford and the rest of the Muppets Tonight gang members.
- At the Juice Bar: Johnny and Sal serve karaoke and watermelon juice at the juice bar.
- Pepe and Seymour's Vacation Jacuzzi: Pepe and Seymour take turns playing 'go fish'.
- Tales from the Vet: Dr. Phil Van Neuter tests out his latest creation, the automatic egg beater
- Musical #: Them Bones, them Dry Bones (sung and performed by Rizzo and the Rest of the Muppets Tonight gang members)
- Muppet Labs: Bunsen and Beaker demonstrate the Automatic Electric Railroad Train Set.
- Grand Finale Musical #: Good Riddance (Time of Your Life) (sung and performed by Jay Leno and the Muppets Tonight gang members)